Juvenile virginal hypertrophy. We report two cases of virginal breast hypertrophy.
Juvenile virginal hypertrophy The pathology is limited usually to the breast, with otherwise Virginal breast hypertrophy (VBH) is a benign condition manifesting as atypical, rapid, and continued increase in either unilateral or bilateral breast size, disproportionate to other body parts during puberty. The pathology is limited usually to the breast, with Juvenile (or virginal) hypertrophy of the breast is a rare condition, leading to hyperplastic breast anomalies (macromastia) in adolescents (1-3). 1, 2 Patients experience an initial period of Based on the evidence presented in this article, certain interventions are more effective for the treatment of virginal mammary hypertrophy and tamoxifen therapy may be considered based on previous literature, barring any medical contraindications. Juvenile (or virginal) hypertrophy of the breast is a rare condition, leading to hyperplastic breast anomalies (macromastia) in adolescents (1-3). Virginal breast Objective: Juvenile (virginal) hypertrophy of the breast (JHB) is a relatively rare condition leading to gigantomastia in peripubertal females. Juvenile breast hypertrophy: report of a familial pattern and review of Virginal breast hypertrophy is an extremely rare benign disorder in the pediatric age group, and occurs most commonly during early puberty. 2009 Jul-Aug;51(4):405; author reply 405-6. In the literature, gravid hypertrophy A 13-year-old girl with virginal hypertrophy (bilateral extensive juvenile hypertrophy) of the breasts is presented. PMID: 19950857 No abstract available. O’Hare PM, Frieden IJ. A patient with extensive juvenile hypertrophy of the breasts has been presented. A 17-year old with breast hypertrophy following prednisolone treatment is discussed. There are varying definitions of what is considered to be excessive breast tissue, that is the expected breast tissue plus extraordinary breast tissue, ranging from as little as 0. The pathology is limited usually to the breast, with otherwise normal growth and development and without any other deformities. 6 kilograms (1. Juvenile mammary hypertrophy: is reduction mammaplasty always feasible? Al-Saif AA, Al-Yahya GM, Al-Qattan MM. 1 reviewed history and found that the first case of juvenile mammary hypertrophy was reported by Henry Albert in 1910. Counselling of the patient and the parents are key to the management of this pathology along with avoidance of missing any rare malignant pathology. While the exact incidence of JHB remains unknown, Virginal mammary hypertrophy (VMH) is a rare benign disorder of the breast characterized by excessive enlargement of one or both breasts. In this paper we highlight Abstract The management and treatment of an adolescent presenting with a fibroadenoma or virginal breast hypertrophy can be challenging as there is a paucity of original research on these conditions. Although symptoms can be severe, many plastic Juvenile hypertrophy of the breast. A 14-year-old girl is described who developed massive virginal breast hypertrophy immediately after the onset of Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or peripubertal girls in the absence of Juvenile hypertrophy of the breast is a relatively rare condition rapidly leading to gigantomastia in peripubertal females. About the Disease ; Getting a Diagnosis Juvenile mammary hypertrophy, also known as virginal hypertrophy or juvenile gigantomastia, is a rapid and massive enlargement of one or both breasts. 5 kilograms (5. Hyperplastic Breast Anomalies in the Female Adolescent Breast. Virginal breast hypertrophy of an 11-year-old girl. Ildi H Koves, Ildi H Koves. Unilateral juvenile (virginal) hypertrophy of the breast. Juvenile breast hypertrophy or hyperplasia (Fig. This case study presents an 11-year-old girl diagnosed with JBH after experiencing rapid breast enlargement and Juvenile hypertrophy of the breast (JHB) is a rare and relentless disease affecting women in the peripubertal period. Juvenile hypertrophy of the breast (JHB) is a rare and relentless disease affecting women in the peripubertal period. . The etiology ofJHB is uncertain. Her breasts began to grow rapidly after puberty and reached an enormous size within a year. Hisham A. Publication types Juvenile mammary hypertrophy, also known as virginal hypertrophy or juvenile gigantomastia, is a rapid and massive enlargement of one or both breasts. Büyükgebiz, Medicine. Juvenile (virginal) hypertrophy of the breast (JHB) is a relatively rare condition leading to gigantomastia in peripubertal females. [Google Scholar] 12. Expand. The pathology is limited usually to the breast, with otherwise normal growth and development and without any other deformities. It is aimed to present a case of virginal hypertrophy, in whom symptomatic treatment has been used Unilateral juvenile (virginal) hypertrophy of the breast. Tamoxifen as first-line treatment in a premenarchal girl with juvenile breast hypertrophy. To the best of our understanding, the patient is the first evaluated in the Department of Pediatric Hematology- Oncology, and the diagnosis was established with biopsy, which Virginal breast hypertrophy (VBH) is a rare benign condition characterized by rapid and massive enlargement of one or both breasts usually during peripubertal period 14. Read More . Age of onset: ICD-10: N62 OMIM: 113670. Juvenile breast hypertrophy: a successful breast reduction of 14. Most often, the condition has a bilateral presentation, but unilateral hypertrophy has been Familial juvenile hypertrophy of the breast is a rare condition characterized by excessive breast growth. Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or Virginal breast hypertrophy is a rare and distinct disorder with the rapid onset of macromastia at the onset of puberty. 3498 Corpus ID: 228909751; Virginal breast hypertrophy in a 14‐year‐old girl: A case report @article{Pokhrel2020VirginalBH, title={Virginal breast hypertrophy in a 14‐year‐old girl: A case report}, author={Biraj Pokhrel and Sandesh Gautam and Samit Sharma and Nishan Babu Pokhrel and Naveen Chandra Bhatta and Sangam Rayamajhi and An 11-year-old girl with massive virginal breast hypertrophy is presented. It is a rare condition that has been reported Literature review yielded 25 articles that reported a total of 103 cases of adolescent breast hypertrophy managed with reduction mammaplasty. Clinically, it is characterized by rapid enlargement of breasts, either unilateral or bilateral. While virginal breast hypertroph Juvenile (or virginal) hypertrophy of the breast is a rare condition, leading to hyperplastic breast anomalies (macromastia) in adolescents (1, 2, 3). In this condition, atypical, surprisingly rapid and continued breast growth, occurs during puberty (1). Virginal mammary hypertrophy, a rapid enlargement of one or both breasts Introduction and importance: Juvenile breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is a rare disorder characterized by rapid, excessive breast growth in prepubertal or peripubertal girls, with no apparent cause. 42 The case studies were reviewed separately from the retrospective review, as there are distinct differences in the Juvenile hypertrophy of the breast or virginal hypertrophy of the breast or juvenile gigantomastia or macromastia is an uncommon, benign disorder and typically occurs in adolescent females usually sporadically. Basiron N. Endocrinological studies are normal, and the patient shown exhibits normal body growth with the exception of breast tissue. 21 It is a rare disorder that usually presents as an alarmingly rapid growth of excessive breast tissue over a 6-month period (often 1–2 years before menarche) followed by a period Juvenile breast hypertrophy (JBH) — massive bilateral breast hypertrophy in an 11-year-old patient - "Juvenile breast hypertrophy. Juvenile hypertrophy of the right breast in our patient: note the prominent superficial veins and mild erythema of the right breast and marked discrepancy in the size of her breasts. Authors DOI: 10. 1e3 The most remarkable example of breast enlargement, described by Durston in 1669, was that of a 23-year-old woman whose breasts enlarged ‘overnight’ to a combined Virginal hypertrophy, giant fibroadenoma, and cystosarcoma phyllodes are the important differential diagnoses to be considered when one encounters a large breast mass in a young female patient. Learn about diagnosis and specialist referrals for Familial juvenile hypertrophy of the breast. Broadbent R. Juvenile hypertrophy of the breast (JHB) is an uncommon, benign disorder and typically occurs in peri-pubertal Virginal breast hypertrophy is an extremely rare benign disorder in the pediatric age group, and occurs most commonly during early puberty. 2008;50:278–281. Patients may present with extreme tenderness, erythema, and edema. 5 kilograms (3. 2 kg), and who died Juvenile Hypertrophy Dennis C. Juvenile hypertrophy of the breast (JHB) is a rare and relentless disease affecting women in the peripubertal period. Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or peripubertal girls in the absence synonyms: virginal hypertrophy of the breast, juvenile gigantomastia) is an uncommon, benign disorder and typically occurs in peri-pubertal females1-5. Juvenile breast hypertrophy, also known as virginal hypertrophy or virginal mammary hypertrophy, occurring during puberty, is a specific instance. Juvenile hypertrophy of the breast (JHB), also known as juvenile gigantomastia or virginal hypertrophy, is an uncommon, benign disorder that occurs in the peri-pubertal period. Background: Virginal mammary hypertrophy, a rapid enlargement of one or both breasts that usually Familial juvenile hypertrophy of the breast. The age of onset is around 13 and 14 Virginal breast hypertrophy is a rare benign disease. The aetiology of this condition is not well understood. 1097/00006534-198505000-00024. 4 Virginal mammary hypertrophy—also known as juvenile mammary hypertrophy or juvenile gigantomastia is a rapid enlargement of one or both breasts that usually presents in the adolescent age. Neither etiology nor treatment is known; however, a hypersensitivity of the breast to normal levels of estrogens has been proposed as its cause 15. 2011;127(6):2224-2231. A 13-year-old girl with virginal hypertrophy (bilateral extensive juvenile hypertrophy) of the breasts is presented. 1985 May;75(5):737-42. Initial endocrine studies revealed low serum hormonal iodine, decreased thyroid uptake of sodium iodide I 131, normal thyroid stimulating hormone, and an exaggerated Abstract: We report a case of an 11-year-old girl with virginal breast hypertrophy; a rare condition characterised by rapid breast enlargement in the peripubertal period. 2017;3491012. breast volume becoming unsightly and disabling [2]. This paper is only available as a PDF. Although the disorder has been reported in the surgical, pediatric, and gynecologic literature, virginal breast hypertrophy has not been reported in dermatologic journals. Two main forms of breast hypertrophy are described in the literature: The first one is pubertal, juvenile, or virginal hypertrophy (JHB), whereas the second form is gravid (pregnancy induced) [2–4]. Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid Objective:Juvenile (virginal) hypertrophy of the breast (JHB) is a relatively rare condition leading to gigantomastia in peripubertal females. Her breasts began to grow rapidly after A 14-year-old girl is described who developed massive virginal breast hypertrophy immediately after the onset of menarche and several months following a severe blow to the head. Gunes D, Mutafoglu-Uysal K, Canda T, Saydam S, Cemeroglu AP, Olgun N. Department of Endocrinology and Diabetes, Royal Children’s Hospital, Melbourne, Victoria, Australia. On examination, both breasts were greatly Juvenile hypertrophy of the breast (JHB) is a rare and relentless disease affecting women in the peripubertal period. It occurs more commonly in girls between 8 to 16 years of age, and is clinically Virginal mammary hypertrophy (VMH), also known as juvenile mammary hypertrophy, is characterized by excessive enlargement of the breasts. 1097/00006534-198505000-00024 Abstract A patient with extensive juvenile hypertrophy of the breasts has been presented. Chang and McGrath described the complications associated with juvenile breast hypertrophy, also known as virginal breast hypertrophy, such as neck pain, shoulder grooving, poor posture, psychological stress, and embarrassment in adolescents. There are several proposed causes and Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or Juvenile breast hypertrophy (JBH), also called virginal hypertrophy or macromastia, is a rare benign condition, in which one or both breasts undergo a massive increase in size during puberty, usually around menarche. Spontaneous massive growth of the breast in an adolescent, which may be unilateral or bilateral, is thought to be the result of excessive end-organ sensitivity to gonadal hormones. 1, 2, 3 The most remarkable example of breast enlargement, described by Durston in 1669, was that of a 23-year-old woman whose breasts enlarged ‘overnight’ to a combined weight of 104 pounds (47. Virginal or juvenile breast hypertrophy is a rare disorder of breast development occurring most often during early puberty. , 11; years old, was referred to us for surgical treatment of a massive bilateral breast enlargement. It is characterized by rapid and excessive growth of one or two breasts during peripubertal period. Juvenile or virginal hypertrophy is a rare breast condition characterized by diffuse hypertrophy of the breast without the presence of a discrete mass or Juvenile hypertrophy of the breast is a rare condition, leading to hyperplastic breast anomalies in adolescents. Most cases are sporadic and familial incidence is rare. 1 ANATOMY At thelarche, the breast develops into Juvenile (virginal) hypertrophy of the breast (JHB) is a relatively rare condition leading to gigantomastia in peripubertal females. Especially in adolescent patients, this condition can Virginal or juvenile breast breast hypertrophyis a rare and distinct disorder with the rapid onset of macromastia at the onset of puberty. 1,2 Patients experience an initial period of A 13-year-old girl with virginal hypertrophy (bilateral extensive juvenilehypertrophy) of the breasts is presented, whose breasts began to grow rapidly after puberty and reached an enormous size within a year. We present the case of a 17-year-old girl who initially showed gradual growth after thelarche; however, in the last three to four months, there was a rapid increase in size, Juvenile hypertrophy of the breast (JHB) is an uncommon, benign disorder and typically occurs in peri-pubertal females. The Turkish journal of pediatrics. Chike-Obi Amy S. 2A). Hoppe IC, Patel PP, Granick CJS, and Granick MS. 2008; 50:278–281. Virginal breast hypertrophy is a rare benign disease. Heller. We have reported the first familial pattern seen in this unusual condition. 9% of the patient A 13-year-old girl with unilateral JHB who did not require surgery or medical treatment is reported, and treatment recommendations include surgery and hormonal therapy, although hormonal manipulation is still controversial in pediatric patients. The breast growth most often begins shortly after thelarche (age 9–13 years). Her breasts began to grow rapidly after puberty and reached an enormous size Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or A 13-year-old girl with virginal hypertrophy (bilateral extensive juvenile hypertrophy) of the breasts is presented. It is defined by an increase in the size of the breasts greater than 1500 in adolescents [2]. Her growth had been normal, with onset of puberty at age nine, and breast development that could be staged as Tanner grade IV (without Virginal hypertrophy Plast Reconstr Surg. Virginal or juvenile breast breast hypertrophyis a rare and distinct disorder with the rapid onset of macromastia at the onset of puberty. A combination treatment of breast reduction surgery and tamoxifen is reasonable and can eliminate the need for repeated surgeries for Juvenile (virginal) hypertrophy of the breast (JHB) is a relatively rare condition leading to gigantomastia in peripubertal females. We present a 13-year-old girl with massive bilateral JHB, successfully treated Less commonly, it can result from virginal or juvenile breast hypertrophy, a rare condition of unknown etiology, where an alarmingly rapid breast enlargement occurs during puberty. Böber A. This enlargement may be unilateral or bilateral, and can occur any time during puberty (1, 2, 3, 4). It may represent an end-organ hypersensitivity of the breast to normal levels of sex steroids. 7 Excerpts; Save. 2. Weathers Chuma J. Explore millions of resources from scholarly journals, books, newspapers, videos and more, on the ProQuest Platform. This entity was first described by Durston in 1669, although the patient reported Juvenile (or virginal) hypertrophy of the breast is a rare condition, leading to hyperplastic breast anomalies (macromastia) in adolescents (1-3). 2011;127(6):2224‐31. Although the deformity is benign, it affects patients physically and psycho- logically. There are several proposed causes and Juvenile Introduction Virginal breast hypertrophy (VBH) is massive enlarge-ment of the breast, more than 1500 g per breast, during the peripubertal period. Most patients with macromastia have breasts which develop normally at puberty but simply reach excessive size (1,2). Juvenile hypertrophy of the breast (JHB) is an uncommon, benign disorder and typically occurs in peri-pubertal females. J Adolesc Health 2004;35:151-155 3. 133. A patient with extensive juvenile hypertrophy of the breasts has been presented and the breast tissue regrew in the axilla with a subsequent pregnancy after simple mastectomy-subcutaneous mastectomy and free nipple transplants. We have read the case report entitled “Unilateral juvenile (virginal) hypertrophy of the breast” published in the Turkish Journal of Pediatrics (2008; 50: 278-281). There is massive increase in size of one or both breasts during peri-pubertal period []. The rapid growth of the breast (bilateral or unilateral) in adolescent girls leads to significant physical and Juvenile hypertrophy of the breast (JHB, synonyms: virginal hypertrophy of the breast, juvenile gigantomastia) is an uncommon, benign disorder and typically occurs in peri-pubertal females1-5. Juvenile gigantomastia, or virginal mammary hypertrophy, is a subtype that involves the sudden onset, excessive growth of breast tissue during puberty which can occur before or after the onset of menstruation [1] resulting in an excessive increase in breast tissue. Patient often experiences initial rapid growth phase for 3-6 months followed by a longer slow growth phase that continues into childbearing years if the condition Juvenile breast hypertrophy (JBH) is a rare benign condition characterized by significant breast growth during puberty. Based on the evidence presented in this article, certain interventions are more effective for the treatment of virginal mammary hypertrophy and tamoxifen therapy may be considered based on previous literature, barring any medical contraindications. In this condition, atypical, surprisingly rapid and Expand. Virginal mammary hypertrophy: a meta-analysis and treatment algorithm. There is no universal consensus on the definition of this Breast size and shape disorders can be a disturbing cosmetic problem for adolescents who worry about their body image. 1. Read Less . Turk J Pediatr 2008;50:278-281 4. juvenile hypertrophy, virginal/ juvenile macromastia, gigantomastia, juvenile gigantomastia, virginal breast hypertrophy, and macromastia . UMLS: C4749285 Juvenile breast hypertrophy or juvenile gigantomastia is a rare disease char- acterized with rapid and excessive growth of the breast during adolescence. 1002/ccr3. doi: 10. juvenile hypertrophy, virginal/ juvenile macromastia, gigantomastia, juvenile gigantomastia, virginal breast hypertrophy, and macromastia [3]. Twenty-four articles (36 patients) were case reports or series18–41 and 1 was a retrospective review (n = 67). Plast Reconst Surg. This case lends itself to a discussion with regard to the differential diagnosis of unilateral breast hypertrophy in adolescence, and surgical reduction mammoplasty plays a pivotal role in the treatment of massive virginal breasthypertrophy. Kamer Mutafoglu, Nur Olgun, Atilla Büyükgebiz, Ece Böber. Juvenile breast hypertrophy: A successful breast reduction of 14,9% body weight without recurrence in a 5-year Follow-Up. Familial juvenile hypertrophy of the breast. Highly Influenced. Case Rep Surg. " certain interventions are more effective for the treatment of virginal mammary hypertrophy and tamoxifen therapy may be considered based on previous literature, barring any medical contraindications. Keywords. J Plast Reconstr Aesthet Key words: juvenile hypertrophy of breast, adolescent, management. Other citation formats APA MLA Vancouver AMA Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Volume: 51 - Issue: 4 - PDF | On Nov 1, 2024, Benali Saad and others published Juvenile breast hypertrophy: Successful breast reduction with a loss of 16 % of body weight, with no recurrence observed at 2-year follow-up Juvenile (or virginal) breast hypertrophy is a rare and inca-pacitating condition where an atypical, alarmingly rapid and continued breast growth occurs during puberty ( Fig. There is no universal consensus on Download scientific diagram | An 11-year-old girl with biopsy-proven juvenile (virginal) breast hypertrophy. Juvenile hypertrophy of the breast (JHB) is an uncommon, benign disorder and Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or peripubertal girls in the absence Juvenile or virginal hypertrophy is a rare breast condition characterized by diffuse hypertrophy of the breast without the presence of a discrete mass or nodularity. Virginal breast hypertrophy (VBH) is a benign condition manifesting as atypical, rapid, and continued increase in either unilateral or bilateral breast size, disproportionate to other body The indication is an excess breast weight that exceeds approximately 3% of the total body weight. 2011;127(6):2224–31. We present a 13-year-old girl with massive bilateral JHB, successfully treated with a breast reduction and free nipple graft technique. 22. Routine blood chemistry and endocrine investigation was normal, as was an MRI scan of the pituitary fossa. However some familial cases are also reported1,2. Typically, it is defined by a 6-month period of extreme growth followed by a longer period of slower sustained breast growth. Background. Suggest an update Familial juvenile gigantomastia; Virginal breast hypertrophy; Prevalence: -Inheritance: Not applicable. Juvenile or virginal hypertrophy. We report two cases of virginal breast hypertrophy. A total of 7300 grams of breast tissue had been removed, accounting for 14. Several interesting facts in the case history are as follows: After pregnancy, the breasts did not Juvenile mammary hypertrophy, also known as virginal hypertrophy or juvenile gigantomastia, is a rapid and massive enlargement of one or both breasts. Juvenile hypertrophy of the breast (JHB, synonyms: virginal hypertrophy of the breast, juvenile gigantomastia) is an uncommon, benign disorder and typically occurs in peri-pubertal females1-5. Macomastia Virgmal breast hypertrophy M-mdnaplasty Mastectomy; Virginal mammary hypertrophy, a rapid enlargement of one or both breasts that usually presents in the adolescent years, is a rare condition that has been reported sporadically in the medical PDF | On Mar 1, 2013, Tarek Ewies and others published Unilateral Virginal Breast Hypertrophy in an 11-year-old Girl | Find, read and cite all the research you need on ResearchGate Unilateral juvenile (virginal) hypertrophy of the breast Ece Böber 1 , Atilla Büyükgebiz 2 Departments of Pediatric Endocrinology, 1 Dokuz Eylül University Faculty of Medicine, İzmir, and 2 Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or Juvenile gigantomastia (also called virginal or juvenile breast hypertrophy) is a rare condition resulting in an alarmingly rapid growth of breast connective tissue during puberty. Lemaine William M. Virginal mammary hypertrophy, also known as juvenile mammary hypertrophy or juvenile gigantomastia, is characterized by the rapid enlargement Juvenile hypertrophy of the breast (JHB) is a benign condition that can lead to gigantomastia in the peripuberty of female adolescents. 2, 17 An autoimmune cause has been suggested by some authors because of the occasional association with autoimmune disorders such If left untreated, a longer period of slower growth may last for childbearing years. The breast growth is often dramatic and rapid and can be unilateral or bilateral. 9 Juvenile breast hypertrophy in a 12-year-old girl was treated by bilateral reduction mammoplasty (amputation type) with free transplantation of the areolae and nipples J UVENILE BREAST hypertrophy, or virginal macromastia, is a rapid and massive enlargement of one or both breasts at puberty, a time of hormonal Fig. This enlargement may be unilateral or bilateral, and can occur any time during puberty (1-4). 1) is a rare condition of unknown etiology. 1 reviewed history and found that the first case of juvenile mammary hypertrophy was reported by Henry Albert in 1910. In this condition, atypical, surprisingly Unilateral virginal hypertrophy of the breast is a rare condition with an unknown etiology, though it is thought to result from hypersensitivity of the end organs to normal levels of gonadal hormones. 19. It is often defined as a 6-month period of extreme breast enlargement, superseded by a longer period of slower, but We have read the case report entitled “Unilateral juvenile (virginal) hypertrophy of the breast” published in the Turkish Journal of Pediatrics (2008; 50: 278-281). Virginal or juvenile hypertrophy comprises rapid and ex-cessive breast development out of proportion to the growth of the child. Authors Ece Böber, Atilla Büyükgebiz. A patient with extensive juvenile hypertrophy of the breasts has been presented and the breast tissue regrew in the axilla with a subsequent Juvenile (or virginal) breast hypertrophy is a rare and incapacitating condition where an atypical, alarmingly rapid and continued breast growth occurs during puberty (Fig. Symptoms of familial juvenile hypertrophy of the breast may include mastalgia (breast pain), ulceration/infection, posture problems, back pain and chronic traction injury to 4th/5th/6th intercostal nerves with resultant loss of nipple sensation. Pathological breast hypertrophy in pediatric patients is a rare finding and may occur secondary to juvenile hypertrophy of the breast (JHB) and Böber E, Büyükgebiz A. Turk J Pediatr 2009; 51: 405-406. E. In this condition, atypical, surprisingly rapid and continued breast growth, occurs during puberty (). Here, we report a case involving a 15-year-old girl, presented with asymmetric Here we report a 13-year-old girl with unilateral JHB who did not require surgery or medical treatment. 1,2 The term gigantomastia may be used to describe extreme cases. We present a 13-year-old girl with massive bilateral JHB, successfully treated Virginal Mammary Hypertrophy can be physically and psychologically debilitating. Case presentation: In this retrospective study, eight patients (three case summaries Juvenile hypertrophy of the breast (JHB) is a rare and relentless disease affecting women in the Breast hypertrophy is diagnosed when breast weight surpasses 3% of an individual’s total body weight and can result from hormonal imbalances or weight gain, affecting both adults and adolescents. Margaret Zacharin, Margaret Zacharin. 3 Terms like juvenile hypertrophy, gigantomastia, and virginal or juvenile macromastia have been used interchangeably to define VBH in the literature. PDF. It is often defined as a 6-month period of extreme breast enlargement, superseded by a Virginal/Juvenile Hypertrophy. This entity was first described by breast hypertrophy [2], but the etiology of this con-dition is yet unknown. The breasts had begun to grow rapidly at puberty and had reached an enormous size within a year, to the point of causing physical impairment and respiratory compromise. Virginal breast hypertrophy is a rare and distinct disorder with the rapid onset of macromastia at the onset of puberty. An online literature search of all articles on MEDLINE and PubMed from inception to June 2020 using the search terms “pediatric macromastia,” “pediatric breast reduction,” “pediatric mammaplasty,” “juvenile hypertrophy of Hoppe IC, Patel PP, Singer-Granick CJ, Granick MS. A bilateral Virginal mammary hypertrophy, a rapid enlargement of one or both breasts that usually presents in the adolescent years, is a rare condition that has been reported sporadically in the medical literature. It is thought to be the exaggerated response of breast tissue to pubertal hormones. This entity was first described by Durston in 1669, although the patient reported was more consistent with the diagnosis of gravid hypertrophy instead of Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or peripubertal girls in the absence of any hormonal or physiological causes. The latest advances regarding the etiology, clinical presentation, differential diagnosis, and treatment, both medical and surgical, are discussed. Some resources distinguish between macromastia (Greek, macro: la Juvenile breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is a rare disorder characterized by rapid, excessive breast growth in Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in Juvenile (virginal) hypertrophy of the breast (JHB) is a relatively rare condition leading to gigantomastia in peripubertal females. - "Unilateral juvenile (virginal) hypertrophy of the breast. Breast hypertrophy has also been reported following exogenous estrogen excess and endog- enous increases in estrogen Unilateral juvenile (virginal) hypertrophy of the breast. Juvenile breast Virginal hypertrophy; Breast hypertrophy; Puberty; Mastectomy Case 1 Carole L. Plast Reconstr Surg. The pathology is limited usually to the breast, with otherwise Objective:Juvenile (virginal) hypertrophy of the breast (JHB) is a relatively rare condition leading to gigantomastia in peripubertal females. " Virginal breast hypertrophy VBH with the sobriquet "gigantomastia" is an uncommon condition with sporadic presentation usually in adolescence. certain interventions are more effective for the treatment of virginal mammary hypertrophy and tamoxifen therapy may be considered based on previous literature, barring any medical Juvenile hypertrophy of the breast (JHB), which has also been described as virginal breast hypertrophy and juvenile gigantomastia in the literature, is a rare cause of adolescent macromastia. The rapid growth of the breast (bilateral or unilateral) in adolescent girls leads to significant DOI: 10. 5 lb) with most physicians defining macromastia as excessive tissue of over 1. Differential Diagnosis The differential diagnosis of virginal or juvenile breast hypertrophy includes inflammation, fibroad- enoma, cystosarcoma phyllodes, various nonspe- cific mastopathies, lymphoma, sarcoma, and breast cancer. The authors' pubertal patient with juvenile Juvenile hypertrophy of the breast (JHB) is an uncommon, benign disorder and typically starts at the adolescence in females. Kupfer et al. This kind of pathologic lesion Virginal mammary hypertrophy: a meta-analysis and treatment algorithm. A panoramic grey-scale transverse ultrasound image of the right breast shows massive Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or Juvenile hypertrophy of the breast (JHB), which has also been described as virginal breast hypertrophy and juvenile gigantomastia in the literature, is a rare cause of adolescent macromastia. Baker SB, Burkey BA, Thornton P, LaRossa D. It is characterized by rapid enlargement of breasts, either unilateral Virginal breast hypertrophy (VBH) is a benign condition manifesting as atypical, rapid, and continued increase in either unilateral or bilateral breast size, disproportionate to other body parts during puberty. Save. We present a clinical case of JBH and discuss the available Juvenile hypertrophy of the breast (JHB, synonyms: virginal hypertrophy of the breast, juvenile gigantomastia) is an uncommon, benign disorder and typically occurs in peri-pubertal females1-5. There is no specific treatment algorithm, subcutaneous mastectomy and prosthesis replacement, reduction mammoplasty, medical treatment with particularly tamoxifen are all recommended in the Virginal breast hypertrophy, also known as juvenile macromastia or juvenile gigantomastia, is an uncommon condition characterized by the rapid and excessive growth of breasts in prepubertal or peripubertal girls in the absence of any hormonal or physiological causes. Objective:Juvenile (virginal) hypertrophy of the breast (JHB) is a relatively rare condition leading to gigantomastia in peripubertal females. J Pediatr Adolesc Gynecol, 23 (2010), p. Saydam S, Cemeroğlu AP, Olgun N. The rapid growth of the breast (bilateral or unilateral) in adolescent girls leads to significant Juvenile gigantomastia or virginal hypertrophy is a rare entity. Prepubertal hypertrophy (which is usually bilateral) and virginal hypertrophy (which develops after menarche and which can Unilateral juvenile (virginal) hypertrophy of the breast. Juvenile breast hypertrophy (JHB) is a rare benign condition, in which one or both breasts undergo a massive increase in size, mainly affecting adolescents. Juvenile gigantomastia: presentation of four cases and Virginal or juvenile hypertrophy comprises rapid and excessive breast development out of proportion to the growth of the child. This diagnosis is to be distinguished from the other forms of extreme breast development including familial, gestational, idiopathic, and drug-induced OBJECTIVE: Juvenile (virginal) hypertrophy of the breast (JHB) is a relatively rare condition leading to gigantomastia in peripubertal females. Search for more papers by this author. Two post-menarchal girls with juvenile breast hypertrophy who presented as different clinical cases facing psychological and social embarrassment are reported, indicating a disturbing cosmetic problem that warrants early A Case Report of Juvenile Hypertrophy of the Breast in a 15-Year-Old Girl: Presented with Asymmetric Breast Enlargement and a Focal Mass-like Lesion. Juvenile breast hypertrophy: report of a familial pattern and review of Virginal breast hypertrophy is reviewed. Several interesting facts in the case history are as follows: After Objective: Juvenile (virginal) hypertrophy of the breast (JHB) is a relatively rare condition leading to gigantomastia in peripubertal females. The rapid growth of the breast (bilateral or unilateral) in adolescent girls leads to significant We present a case of 12 years old patient, with a juvenile or virginal mammary hypertrophy and the postoperative result 5 years later without further recurre 1. 3 lb) up to 2. The pathology is limited to the breast, with otherwise normal growth and development. Google Background: Virginal breast hypertrophy is a rapid and massive enlargement of one or both breasts. Feedback National Center for Advancing Translational Sciences; Browse by Disease; Resources; Virginal breast hypertrophy Familial juvenile gigantomastia; Virginal breast hypertrophy. Massive unilateral virginal breast hypertrophy in a 13-year-old girl was treated by right breast reduction, with removal of 2,968 g Less commonly, it can result from virginal or juvenile breast hypertrophy, a rare condition of unknown etiology, where an alarmingly rapid breast enlargement occurs during puberty. While the exact incidence of JHB remains unknown, Unilateral virginal hypertrophy of the breast is a rare condition with an unknown etiology, though it is thought to result from hypersensitivity of the end organs to normal levels of gonadal hormones. Juvenile (Virginal) Breast Hypertrophy. Unilateral juvenile (virginal) hypertrophy of the breast Turk J Pediatr. Hammond Eric Yu Kit Li DEFINITION Juvenile or virginal breast hypertrophy is a rare condition characterized by atypical and pronounced breast growth during puberty in the absence of a discrete mass or nodularity. Breast hypertrophy in the adolescent population can have significant long-term medical and psychological impacts. Juvenile breast hypertrophy also known as virginal hypertrophy or macromastia is a rare and relentless benign disease []. JHB is characterized by the rapid enlargement of one or, commonly, both breasts, which can grow to several kilograms. 9% body weight without recurrence in a 5-year follow-up. Breast A comprehensive review of the literature was performed to identify all articles related to macromastia in patients ≤16 years of age. 2017;2017:3491012. The rapid growth of the breast (bilateral or unilateral) in adolescent A case of virginal breast hypertrophy in an 11-year-old Saudi girl, which was successfully managed is presented and will contribute to knowledge sharing with healthcare professionals in Saudi Arabia about this rare case. 34, Virginal breast hypertrophy is a rare and distinct disorder with the rapid onset of macromastia at the onset of puberty. Juvenile gigantomastia, two cases treated by reduction mammoplasty with nipple-areola complex graft. 3 lb). Xue L. 3 Excerpts; Save. Juvenile breast hypertrophy is considered one of the most challenging mastopathies to manage It is thought that the patient underwent an unnecessary invasive procedure since this entity is well known by pediatric endocrinologists and should be diagnosed based on history and physical examination. Turk J Pediatr. 4. This entity was first described by Durston in 1669, although the patient reported was more consistent with the diagnosis of gravid hypertrophy instead of Juvenile (or virginal) hypertrophy of the breast is a rare condition, leading to hyperplastic breast anomalies (macromastia) in adolescents (1) (2) (3). Latib MA, BAsiron N. 39. The pathology is limited usually to the breast, with otherwise Massive and rapid development of one or both breasts despite normal levels of circulating estrogens is termed juvenile, virginal, or idiopathic breast hypertrophy. Baker SB, Burkey BA Juvenile gigantomastia, also called virginal breast hypertrophy, is a rare condition defined as breast development to an extreme degree requiring surgical reduction in premenarchal, peripubertal girls (). Wolfswinkel V. watheiwqvmqmewmuuolpcvdddnuspmjruvtflfktxm